What is Imvaggis?
Imvaggis is a soft vaginal pessary used in the treatment of vaginal symptoms due to an oestrogen deficiency in postmenopausal women. It contains a low dose of semi-synthetic estriol as an active ingredient. It is the same as the estriol that is produced naturally in the body.10,11
How does Imvaggis work?
Imvaggis is an ultra-low dose oestrogen, it works by replacing the oestrogen which is produced naturally in the body. It is placed into the vagina where it works locally where it is needed.10
How is Imvaggis supplied?
Imvaggis is supplied in a pack with 24 vaginal pessaries. Each pessary is individually wrapped and comes in an aluminium strip of pessaries with tear-off perforations for ease of use. At a maintenance dose of one pessary twice a week, this equates to 12 weeks of use.11
What does 0.03mg mean?
The 0.03mg refers to the amount of estriol in each pessary. Estriol is the active ingredient in Imvaggis that replaces the natural oestrogen produced in the body.10
What is the recommended dose of Imvaggis?
For the treatment of vaginal atrophy, it is recommended to use one pessary daily for the first three weeks and thereafter one pessary twice a week for as long as needed to alleviate symptoms. Your doctor may assess your treatment on an annual basis.10,11
What do I do if I miss a dose of Imvaggis?10
If you forget to use Imvaggis during the first three weeks of treatment you should skip the missed dose and continue with the usual daily dosing schedule.
If you miss a dose after the first three weeks of treatment during the twice weekly use, please make up for the scheduled dose as soon as possible.
Why doesn’t Imvaggis have an applicator?
Imvaggis does not have an applicator as some women may find the use of an applicator uncomfortable. Imvaggis is designed to be inserted into the vagina using a finger.10,11
Is there a discharge after using Imvaggis?
Experiencing vaginal discharge is uncommon. If you do experience some discharge we recommend wearing a panty liner after inserting Imvaggis into the vagina.
What is the source of estriol in Imvaggis?
The Estriol used in Imvaggis is made from yams or soya and is chemically identical to human estriol which is produced naturally in the body.12
How quickly will Imvaggis take to work?
Allow three months for effective symptom control. If you don’t feel your symptoms are improving, please speak to your doctor.3
What is the shelf life of Imvaggis?
Imvaggis has a shelf life of three years.11
How should I store my Imvaggis?
Imvaggis should be stored below 25⁰C.11
How often should treatment with Imvaggis be reviewed?
During treatment with Imvaggis, periodic annual check-ups should take place. The frequency and nature of the examinations should be adapted to the individual risks of the woman. As with all oestrogen-based products, a careful appraisal of the risks and benefits should be undertaken at least annually. Therapy should only be continued if the benefit outweighs the risk.11